Medical Notice

Prescription medications. Tirzepatide is FDA-approved for T2D and obesity. Retatrutide is investigational, Phase 3, and has not been reviewed or approved by FDA. Full disclosure and informed consent are required. Individual results vary.

___
GLP-1 / GIP Medical Weight Loss · Ann Arbor

The Biology of Fat Loss Finally Addressed.

GLP-1 and GIP receptor agonist therapy works where willpower cannot, at the level of the brain, the gut, and the metabolic system simultaneously. Tirzepatide is FDA-approved for obesity and delivers dual-receptor activation that single GLP-1 agents cannot match. It is one of the most clinically validated fat loss medications available and is provided as part of Arbour Longevity’s comprehensive medical weight loss program.
  • Tirzepatide, FDA approved
  • GLP-1 + GIP Dual Agonist
  • Clinician-Prescribed & Supervised
  • Retatrutide, investigational triple agonist
___
GLP-1 / GIP Medications at Arbour Longevity

Every Medication. Every Regulatory Status. Fully Disclosed.

FDA-Approved: T2D & Obesity

GLP-1 / GIP Dual Agonist · Gold Standard

Tirzepatide

Mounjaro® (T2D) · Zepbound® (Obesity) · Compounded versions available

Tirzepatide is the most clinically studied and FDA-approved GLP-1/GIP dual agonist for weight loss. Its simultaneous activation of both GLP-1 and GIP receptors produces appetite reduction, improved insulin sensitivity, slowed gastric emptying, and metabolic effects that single GLP-1 agonists cannot fully replicate. Phase 3 clinical trials demonstrated highly significant body weight reduction outcomes across diverse patient populations. It is the first-line medication in Arbour Longevity's weight loss program for eligible patients.

  • FDA-approved for type 2 diabetes (Mounjaro®) and chronic weight management (Zepbound®). Compounded tirzepatide prescribed under applicable 503A/503B regulations. Brand-name formulations also available. Contraindications, including personal/family history of medullary thyroid carcinoma and MEN 2, reviewed at consultation.

Typical Administration

Subcutaneous injection · Weekly · Titrated from starting dose under clinician supervision · Patient self-administered

Phase 3 Trials: Not Reviewed or Approved by FDA

GLP-1 / GIP / Glucagon Triple Agonist · Investigational

Retatrutide

Triple Agonist · Investigational Compound · Phase 3 Clinical Trials

Retatrutide adds glucagon receptor agonism to the dual GLP-1/GIP mechanism, potentially increasing energy expenditure beyond what appetite suppression alone achieves. Phase 2 trial data demonstrated body weight reduction outcomes that represent some of the highest figures recorded in pharmaceutical trials to date. It is currently in Phase 3 trials. This compound has not received FDA approval. It is prescribed as an investigational compound with comprehensive informed consent.

  • ⚠ INVESTIGATIONAL, has not been reviewed or approved by FDA. Phase 3 clinical trials ongoing. Prescribed at Arbour Longevity as an investigational compound following comprehensive evaluation, full regulatory and evidence disclosure, risk discussion, and written informed consent. Compounding availability is subject to current regulations.

Typical Administration

Subcutaneous injection · Weekly · Clinician-supervised titration required · Patient self-administered

FDA-Approved: T2D · Weight-program use not reviewed or approved by FDA

Biguanide · Insulin Sensitizer · Metabolic Support

Metformin

Glucophage® · Established metabolic medication

Metformin is one of the most studied medications in metabolic medicine, improving insulin sensitivity, reducing hepatic glucose production, and supporting metabolic efficiency. In weight loss programs it may be used adjunctively to address insulin resistance that limits fat loss, particularly in patients with metabolic syndrome, pre-diabetes, or PCOS. Use in weight management has not been reviewed or approved by FDA and is disclosed at consultation.

Typical Administration

Oral tablet · Daily or twice daily · Titrated to minimize GI side effects

FDA-Approved: Epilepsy/Migraine · Adjunct use not reviewed or approved by FDA

Anticonvulsant · Appetite Modulation Adjunct

Topiramate

Topamax® · Weight Loss Adjunct When Indicated

Topiramate is FDA-approved for epilepsy and migraine prophylaxis and is used as an appetite modulation adjunct in weight management programs, a use that has not been reviewed or approved by FDA. It may enhance the appetite-reducing effects of GLP-1 therapy in select patients. It is used at Arbour Longevity only when clinically indicated based on individual patient profile, not as a routine component of every program. Full disclosure of FDA status and risk discussion occur at consultation.

Typical Administration

Oral tablet · Low-dose · Used when clinically indicated · Titrated under supervision

Adjunct Protocols, Supporting Every Weight Loss Program

B12 Injections · Metabolic IV · Tesamorelin

B12 Injections

Methylcobalamin injections support cellular energy metabolism and neurological function, addressing the fatigue that often accompanies caloric restriction and metabolic change. Available weekly or bi-weekly during your program.

Metabolic IV Therapy

Our Metabolic Reset IV delivers the B-Complex, Alpha Lipoic Acid, L-Carnitine, and Magnesium most depleted during active weight loss, supporting metabolic function, energy, and helping prevent the micronutrient deficiencies that slow progress.

Tesamorelin

A GHRH analogue FDA-approved for HIV-associated lipodystrophy, used for visceral adipose tissue reduction, a use that has not been reviewed or approved by FDA. May specifically target metabolically active abdominal fat when GLP-1 therapy alone is insufficient. Full disclosure of FDA status at consultation.

GLP-1 / GIP Therapy · Ann Arbor

The Fat Loss Results You Stopped Believing Were Possible.

Schedule a GLP-1 consultation at Arbour Longevity. We review your metabolic history, current health status, and prescribe the protocol that is clinically appropriate, with complete transparency about every medication, its evidence, and its regulatory status.

Schedule GLP-1 Consultation← Weight Loss Overview
Tirzepatide FDA-approved · All medications clinician-prescribed after comprehensive evaluation · Informed consent required

What GLP-1 therapy costs here

We publish our prices. Most clinics in Ann Arbor do not — you have to book a consultation to find out what you would be paying.

$299
per month
2.5–5 mg
Starting and early titration doses. Where most patients begin.
$450
per month
5–7.5 mg
Mid-range therapeutic dosing as tolerance builds.
$599
per month
7.5 mg and above
Higher therapeutic dosing for patients who need it.

The medication is included in the monthly fee.

That matters more than the headline number. Most clinics quote a program fee and then bill medication separately. We don’t do that — the price you see includes your medication. There is nothing to add on here — the figure above is what you pay.

Your first visit is $35, and it is applied toward your treatment plan. HSA and FSA funds are accepted.

What you are actually paying for

There are cheaper GLP-1 programs than ours. It is worth understanding what has been removed to get the price down.

A clinician, in a room, who knows your history

Prescribed and managed by Gandhi Bhattarai, FNP-BC, PMHNP-BC — triple board certified, and the owner of the practice. Not a form you fill in, not a prescriber you never meet, not a different person each time.

Labs before anything is prescribed

Comprehensive metabolic panel, hormone levels, thyroid, inflammation markers and insulin resistance indicators. Then a lab review at six to twelve weeks, with the protocol adjusted to what your results actually show rather than to a fixed schedule.

Health coaching, included

An in-house certified health coach, clinician-led lifestyle counseling and dietitian referral coordination are part of the program, not an upsell. The medication changes appetite. Coaching is what determines whether the change holds once the medication stops.

Medication from a pharmacy that purity-tests its product

We know where what we prescribe comes from and we can tell you. Ask any provider the same question — who is supervising this, and where does the medication come from. The answers vary more than people expect.

A cheaper program is usually cheaper because there is no examination, no lab work, no coaching and nobody accountable for the outcome. That is a reasonable trade for some people. It should just be a choice you make knowingly rather than one you discover later. If you are searching locally, we also have a page on semaglutide in Ann Arbor.