The Biology of Fat Loss Finally Addressed.
- Tirzepatide, FDA approved
- GLP-1 + GIP Dual Agonist
- Clinician-Prescribed & Supervised
- Retatrutide, investigational triple agonist
Every Medication. Every Regulatory Status. Fully Disclosed.
GLP-1 / GIP Dual Agonist · Gold Standard
Tirzepatide
Mounjaro® (T2D) · Zepbound® (Obesity) · Compounded versions available
Tirzepatide is the most clinically studied and FDA-approved GLP-1/GIP dual agonist for weight loss. Its simultaneous activation of both GLP-1 and GIP receptors produces appetite reduction, improved insulin sensitivity, slowed gastric emptying, and metabolic effects that single GLP-1 agonists cannot fully replicate. Phase 3 clinical trials demonstrated highly significant body weight reduction outcomes across diverse patient populations. It is the first-line medication in Arbour Longevity's weight loss program for eligible patients.
- FDA-approved for type 2 diabetes (Mounjaro®) and chronic weight management (Zepbound®). Compounded tirzepatide prescribed under applicable 503A/503B regulations. Brand-name formulations also available. Contraindications, including personal/family history of medullary thyroid carcinoma and MEN 2, reviewed at consultation.
Typical Administration
Subcutaneous injection · Weekly · Titrated from starting dose under clinician supervision · Patient self-administered
GLP-1 / GIP / Glucagon Triple Agonist · Investigational
Retatrutide
Triple Agonist · Investigational Compound · Phase 3 Clinical Trials
Retatrutide adds glucagon receptor agonism to the dual GLP-1/GIP mechanism, potentially increasing energy expenditure beyond what appetite suppression alone achieves. Phase 2 trial data demonstrated body weight reduction outcomes that represent some of the highest figures recorded in pharmaceutical trials to date. It is currently in Phase 3 trials. This compound has not received FDA approval. It is prescribed as an investigational compound with comprehensive informed consent.
- ⚠ INVESTIGATIONAL, has not been reviewed or approved by FDA. Phase 3 clinical trials ongoing. Prescribed at Arbour Longevity as an investigational compound following comprehensive evaluation, full regulatory and evidence disclosure, risk discussion, and written informed consent. Compounding availability is subject to current regulations.
Typical Administration
Subcutaneous injection · Weekly · Clinician-supervised titration required · Patient self-administered
Biguanide · Insulin Sensitizer · Metabolic Support
Metformin
Glucophage® · Established metabolic medication
Metformin is one of the most studied medications in metabolic medicine, improving insulin sensitivity, reducing hepatic glucose production, and supporting metabolic efficiency. In weight loss programs it may be used adjunctively to address insulin resistance that limits fat loss, particularly in patients with metabolic syndrome, pre-diabetes, or PCOS. Use in weight management has not been reviewed or approved by FDA and is disclosed at consultation.
Typical Administration
Oral tablet · Daily or twice daily · Titrated to minimize GI side effects
Anticonvulsant · Appetite Modulation Adjunct
Topiramate
Topamax® · Weight Loss Adjunct When Indicated
Topiramate is FDA-approved for epilepsy and migraine prophylaxis and is used as an appetite modulation adjunct in weight management programs, a use that has not been reviewed or approved by FDA. It may enhance the appetite-reducing effects of GLP-1 therapy in select patients. It is used at Arbour Longevity only when clinically indicated based on individual patient profile, not as a routine component of every program. Full disclosure of FDA status and risk discussion occur at consultation.
Typical Administration
Oral tablet · Low-dose · Used when clinically indicated · Titrated under supervision
B12 Injections · Metabolic IV · Tesamorelin
B12 Injections
Methylcobalamin injections support cellular energy metabolism and neurological function, addressing the fatigue that often accompanies caloric restriction and metabolic change. Available weekly or bi-weekly during your program.
Metabolic IV Therapy
Our Metabolic Reset IV delivers the B-Complex, Alpha Lipoic Acid, L-Carnitine, and Magnesium most depleted during active weight loss, supporting metabolic function, energy, and helping prevent the micronutrient deficiencies that slow progress.
Tesamorelin
A GHRH analogue FDA-approved for HIV-associated lipodystrophy, used for visceral adipose tissue reduction, a use that has not been reviewed or approved by FDA. May specifically target metabolically active abdominal fat when GLP-1 therapy alone is insufficient. Full disclosure of FDA status at consultation.
GLP-1 / GIP Therapy · Ann Arbor
The Fat Loss Results You Stopped Believing Were Possible.
Schedule a GLP-1 consultation at Arbour Longevity. We review your metabolic history, current health status, and prescribe the protocol that is clinically appropriate, with complete transparency about every medication, its evidence, and its regulatory status.
What GLP-1 therapy costs here
We publish our prices. Most clinics in Ann Arbor do not — you have to book a consultation to find out what you would be paying.
The medication is included in the monthly fee.
That matters more than the headline number. Most clinics quote a program fee and then bill medication separately. We don’t do that — the price you see includes your medication. There is nothing to add on here — the figure above is what you pay.
Your first visit is $35, and it is applied toward your treatment plan. HSA and FSA funds are accepted.
What you are actually paying for
There are cheaper GLP-1 programs than ours. It is worth understanding what has been removed to get the price down.
A clinician, in a room, who knows your history
Prescribed and managed by Gandhi Bhattarai, FNP-BC, PMHNP-BC — triple board certified, and the owner of the practice. Not a form you fill in, not a prescriber you never meet, not a different person each time.
Labs before anything is prescribed
Comprehensive metabolic panel, hormone levels, thyroid, inflammation markers and insulin resistance indicators. Then a lab review at six to twelve weeks, with the protocol adjusted to what your results actually show rather than to a fixed schedule.
Health coaching, included
An in-house certified health coach, clinician-led lifestyle counseling and dietitian referral coordination are part of the program, not an upsell. The medication changes appetite. Coaching is what determines whether the change holds once the medication stops.
Medication from a pharmacy that purity-tests its product
We know where what we prescribe comes from and we can tell you. Ask any provider the same question — who is supervising this, and where does the medication come from. The answers vary more than people expect.
A cheaper program is usually cheaper because there is no examination, no lab work, no coaching and nobody accountable for the outcome. That is a reasonable trade for some people. It should just be a choice you make knowingly rather than one you discover later. If you are searching locally, we also have a page on semaglutide in Ann Arbor.



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