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What We Test: Advanced Diagnostics
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Advanced Diagnostics · ARBOUR Longevity

The Tests That Find What Others Miss.

Standard medicine tests for disease. Arbour Longevity tests for dysfunction, the biological terrain between optimal health and diagnosable illness where most chronic suffering lives. Our diagnostic toolkit includes four advanced panels that reveal what standard labs cannot: the DUTCH test, organic acids testing, genomic panel, and comprehensive standard labs run with functional reference ranges.
  • DUTCH Hormone Metabolites
  • Organic Acids (OAT)
  • Genomic Panel (MTHFR + SNPs)
  • Standard Labs · Functional Ranges
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The Arbour Longevity Diagnostic Toolkit

Advanced Testing That Changes Clinical Decisions.

DUTCH Test

Dried Urine Test for Comprehensive Hormones · Precision Analytical

The DUTCH test is the most comprehensive hormone metabolite panel available, measuring not just hormone levels but the specific pathways through which they are produced, metabolized, and cleared. It captures the full cortisol diurnal curve, estrogen and testosterone metabolites, progesterone, DHEA, melatonin, and organic acid markers for neurotransmitter metabolism. A single standard blood draw for hormones provides a fraction of this picture.

What it reveals that standard labs miss: Cortisol rhythm dysfunction (not just a single level) · Estrogen metabolite pathway (protective vs. carcinogenic) · Androgen conversion and clearance · Methylation capacity indicators · Neurotransmitter metabolism markers · DHEA-cortisol balance across the day

Organic Acids Test (OAT)

Comprehensive Metabolic Assessment · Great Plains / Mosaic Diagnostics

The organic acids test provides a systemic snapshot of metabolic function, measuring the organic acid byproducts of cellular metabolism in urine to reveal mitochondrial function, nutrient cofactor sufficiency, detoxification capacity, neurotransmitter metabolism, intestinal microbial activity, and oxidative stress burden. It is one of the highest-yield single panels in functional medicine practice.

What it reveals: Mitochondrial energy cycle function (Krebs cycle markers) · Vitamin and mineral cofactor depletion (B vitamins, CoQ10, magnesium) · Neurotransmitter metabolites · Detoxification pathway efficiency · Fungal and bacterial dysbiosis markers · Oxidative stress burden

Genomic Panel

MTHFR · Key SNPs · Functional Genomics

Arbour Longevity's genomic panel assesses the single nucleotide polymorphisms (SNPs) most clinically relevant to functional medicine, including MTHFR variants affecting methylation and B vitamin metabolism, COMT affecting catecholamine and estrogen clearance, detoxification SNPs affecting toxin processing, and inflammation variants affecting immune regulation. Genomic findings inform every other element of your functional medicine protocol.

Key variants assessed: MTHFR C677T and A1298C (methylation, B vitamins, homocysteine) · COMT (dopamine, estrogen metabolism) · GSTP1, SOD2 (detoxification and oxidative stress) · VDR (vitamin D metabolism) · Additional variants based on clinical picture

Standard Labs, Functional Reference Ranges

CBC · CMP · Thyroid · Hormones · Inflammatory Markers

Standard labs at Arbour Longevity are ordered comprehensively and interpreted through functional reference ranges, the narrower ranges associated with optimal health rather than the wide reference ranges designed to identify disease. The same CBC and CMP that looks "normal" through a disease lens often reveals significant functional findings when evaluated against optimal ranges. Full thyroid panel (TSH, Free T3, Free T4, Reverse T3, TPO/TgAb), advanced cardiovascular markers (hsCRP, ApoB), sex hormones, vitamin D, B12, ferritin, and fasting insulin are included in the Arbour Longevity standard workup.

What's included: Full thyroid panel · Sex hormones · Fasting insulin · hsCRP · ApoB · Vitamin D · B12 · Folate · Ferritin · CBC / CMP · Lipid panel · Additional markers as clinically indicated

How the Testing Panels Connect

The Panels Are Not

Used in Isolation.

Arbour Longevity's diagnostic approach is system-oriented, not symptom-oriented. A patient presenting with brain fog may receive the OAT for mitochondrial status, the DUTCH for cortisol mapping, the genomic panel for methylation variants, and standard labs for thyroid and nutrient status, because brain fog has multiple biological causes and a single panel addresses only one dimension of the picture.

Not every patient requires every panel. Testing is clinician-selected based on your specific health history, symptom pattern, and clinical picture. The result is a diagnostic strategy that is both comprehensive and targeted, not an expensive panel ordered indiscriminately.

Gut Health · Ann Arbor

Heal the Gut. Change Everything Downstream.

Schedule a gut health consultation at Arbour Longevity. We run the comprehensive assessment, identify what is disrupted, and build the targeted protocol, then follow up to confirm it's working.

  • Pricing at Consultation
  • OAT · Food Sensitivity
  • Telehealth Follow-Up (MI)