In this guide

O-Shot in Ann Arbor, MI | Restore Intimacy Naturally

Key takeaways
  • The O-Shot is a same-visit PRP procedure that uses your own platelets to help rebuild clitoral and vaginal tissue.
  • It is used for reduced sensation, arousal difficulty, dryness, painful sex and mild stress urinary leakage.
  • Results build over 6 to 12 weeks and commonly last 12 to 18 months; some women are offered up to three sessions.
  • Evidence is growing but the studies are small, so results vary and no outcome is guaranteed.
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The O-Shot (Orgasm Shot) is a regenerative PRP (platelet-rich plasma, a concentrate of your own blood platelets) procedure for women with sexual dysfunction, vaginal dryness, low libido, reduced sensitivity, or stress urinary incontinence. At Arbour Longevity in Ann Arbor, Michigan, the O-Shot is given within a full clinical framework. We consider your hormone health, blood-vessel health, and overall wellness, not just the symptom on its own.

This is the main guide. If you have a narrower question, one of these companion articles may answer it faster:

What Is the O-Shot and How Does It Work?

The O-Shot, short for Orgasm Shot, is a non-surgical, same-visit procedure. It uses platelet-rich plasma from your own blood to prompt tissue repair in the clitoral and vaginal region. It applies the same biology used in orthopedic and aesthetic PRP therapy: concentrated growth factors trigger cell repair, collagen (the protein that keeps tissue firm) production, and better tissue function.

It is not a drug. It contains no synthetic hormones, no foreign substances, and no chemical compounds. Every component comes from your own bloodstream.

Because every component is your own, the biology doing the work is your own repair system, concentrated and placed where it is needed. A 2026 systematic review (a study that pools the results of many trials) in The Journal of Sexual Medicine pooled 18 studies covering 480 women, 401 of them treated with PRP. It reported gains in sexual function, symptoms, and vaginal health, with side effects that were few and mild (De Ponte et al., 2026; doi:10.1093/jsxmed/qdaf307). That is a promising showing for a same-visit procedure, and it fits what we see in patients here, though the studies remain small.

What does PRP therapy have to do with the O-Shot?

PRP therapy has been used in regenerative medicine for decades. The idea is simple: your blood contains platelets that carry concentrated growth factors, the proteins responsible for tissue healing, collagen production, cell repair, and better blood flow.

When those growth factors are concentrated and placed into a specific area of the body, they speed up the body's natural repair process in that tissue. In orthopedics, PRP is used for joint repair. In aesthetics, it is used for skin renewal; the Vampire Facelift applies the same platelet biology to the face. In the O-Shot, those same repair signals are applied to vaginal and clitoral tissue to support sensitivity, lubrication, and function.

How is platelet-rich plasma prepared?

The process begins with a standard blood draw, the same as any routine lab visit. That sample goes into a centrifuge, a device that spins at high speed to separate the blood into its parts. The result is a concentrated layer of platelet-rich plasma sitting above the red blood cells. This PRP is drawn into a syringe and prepared for injection. The whole preparation happens in-office, during your appointment, and takes only a few minutes.

How do growth factors trigger tissue repair?

Once placed in the target tissue, the growth factors in the PRP start a cascade of biological activity. They signal the body to make new collagen, promote the growth of new blood vessels (a process called angiogenesis), and prompt the repair cells already present in the local tissue. Over time this can mean thicker tissue, better blood supply, more nerve sensitivity, and better natural lubrication. The response is gradual and builds up; the body is rebuilding, not just reacting to a stimulant.

What Happens During an O-Shot Procedure at Arbour Longevity?

At Arbour Longevity, the O-Shot is performed by Gandhi Bhattarai, FNP-BC, PMHNP-BC, a Triple Board Certified Clinician in Family Medicine, Psychiatry, and Anti-Aging & Regenerative Medicine. Arbour Longevity is a CMA-licensed provider for the O-Shot, which sets the clinic apart from medspas offering unlicensed or unverified PRP services.

Your appointment begins with a private first visit covering your medical history, hormone status, symptoms, and goals. The procedure itself follows a clear, comfortable sequence.

Is the O-Shot painful? What to expect step by step

Discomfort is minimal. A numbing cream is applied to the treatment area well before the injection to keep you as comfortable as possible. Most patients report feeling only mild pressure during the procedure, not pain. Here is what the process looks like from start to finish:

  • Blood draw: A small amount of blood is drawn from your arm, like a routine lab test.
  • PRP preparation: The sample is placed in the centrifuge in-office and spun down to isolate the platelet-rich plasma.
  • Numbing cream: A numbing cream is applied to the clitoral and vaginal area and given time to take full effect.
  • Injection: The concentrated PRP is carefully placed into the clitoral region and the front vaginal wall (the area linked to the G-spot and urethral support).
  • Recovery: There is no downtime. Most patients return to normal activity the same day.

How long does the O-Shot procedure take?

From start to finish, the whole appointment often takes 45 to 60 minutes, including the first visit, blood draw, PRP preparation, and the procedure itself. Because it is a same-visit treatment, there is no need for several pre-procedure appointments or long preparation steps.

Wondering whether the O-Shot fits what has changed for you?
A private 30-45 minute first visit that reviews your hormones, tissue and goals before anything is booked, with the $35 applied toward your plan.
Book your $35 first visit Call (734) 436-3357

What Conditions Can the O-Shot Treat?

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The O-Shot is not a single-symptom fix. Its repair mechanism addresses several overlapping concerns that affect female sexual health, pelvic function, and intimate wellness. Women seek the O-Shot for a range of reasons, from reduced arousal after childbirth to vaginal dryness after menopause.

Six-tile map of O-Shot concerns: arousal, libido, dryness, painful intercourse, stress incontinence, postpartum change
The O-Shot targets tissue quality: arousal and sensitivity, dryness, discomfort, mild stress incontinence and postpartum change.

Knowing what the O-Shot can address helps clarify whether it is the right starting point for your concerns.

Can the O-Shot help with low libido and arousal difficulty?

Low libido (sex drive) and difficulty with arousal are among the most common and least discussed concerns in women's sexual health. They are not simply psychological. Reduced blood flow to the clitoral and vaginal tissue, hormone shifts, and tissue thinning all contribute to a measurable drop in physical arousal response.

The O-Shot targets this at the tissue level. By supporting blood supply and nerve sensitivity in the clitoral region, it aims to improve arousal response, desire, and ease of reaching orgasm. Many women report a meaningful change; results vary from person to person. If desire itself is the main problem and sensation is intact, start with why low libido in women has many causes.

How does menopause affect female sexual function?

Menopause (the point one year after your last period) brings a sharp drop in estrogen (the main female sex hormone) and testosterone. Both hormones directly support vaginal tissue health, lubrication, and sexual response. As estrogen drops, the vaginal walls become thinner, drier, and less elastic, a condition known as vaginal atrophy. Sensitivity drops. Arousal becomes slower and less reliable. Intercourse can become uncomfortable or painful.

At Arbour Longevity, the O-Shot is often assessed alongside hormone optimization, including BHRT (bioidentical hormone replacement therapy). Tissue that is starved of estrogen has less to work with, so addressing the hormone setting first gives the PRP a better chance to help. This is the clinical difference a whole-person framework offers.

Does the O-Shot treat stress urinary incontinence?

Yes, and this is one of the better-supported uses of the O-Shot. Stress urinary incontinence (SUI) is leaking urine during physical activity, coughing, sneezing, laughing, or exercise. It is caused by weakened pelvic floor support and thinned urethral tissue, often after childbirth, hormone changes, or aging.

The PRP placed during the O-Shot prompts tissue repair along the front vaginal wall, which supports the urethra. As the tissue thickens over the weeks after treatment, many women report fewer leaks. For women who have been managing this quietly, avoiding workouts, planning around bathrooms, or simply accepting it, the O-Shot offers a non-surgical path with randomized-trial support behind it.

Bladder leakage is a deep enough topic to have its own page. The O-Shot for stress urinary incontinence covers the randomized, sham-controlled trial evidence, how an incontinence course is spaced, and where surgery is still the better option.

Can the O-Shot relieve vaginal dryness and painful intercourse?

Vaginal dryness and dyspareunia (painful intercourse) are directly tied to tissue health and natural lubrication. Both are common during perimenopause and menopause but can also occur in younger women because of hormone imbalance, postpartum changes, or certain medications.

The growth factors delivered through the O-Shot support thicker vaginal tissue, better gland function, and more natural lubrication over time. Many patients report better comfort during intercourse within several weeks of treatment, with further change as the repair process matures. Pain during sex has several possible causes and is worth working through properly; sexual pain in women is treatable sets out what else to rule out first.

Who Is an Ideal Candidate for the O-Shot?

The O-Shot suits a broad range of women with changes in sexual function or pelvic health. You may be a strong candidate if you have any of the following:

  • Reduced sexual sensitivity or difficulty reaching orgasm
  • Low libido or reduced sexual desire
  • Vaginal dryness, especially after menopause or hormone changes
  • Painful intercourse (dyspareunia)
  • Stress urinary incontinence: leaking with coughing, sneezing, or exercise
  • Postpartum changes in sensation or vaginal tissue tone
  • Sexual arousal disorder or difficulty becoming physically aroused
  • A wish to improve sexual satisfaction and confidence in intimacy

The O-Shot suits women across a wide age range, from those with postpartum changes in their 30s to women in perimenopause and menopause in their 40s, 50s, and beyond.

Those two life stages involve different tissue changes and different treatment orders. If one of them is your reason for reading, see the O-Shot after childbirth and after menopause, which explains what changes in each case and why hormones come first after menopause.

Who should avoid the O-Shot?

The O-Shot is well tolerated by most, but it is not right for everyone. A full first visit with Gandhi at Arbour Longevity will decide whether the treatment is right for you. Reasons not to treat may include active infection in the treatment area, blood clotting disorders, active cancer, or certain platelet problems. This is exactly why the O-Shot at Arbour Longevity begins with a full clinical assessment, not a simple booking form.

If you would like to work through this before your visit, our screening guide to O-Shot candidacy, who it helps and who it does not, sets out the concerns it matches best, the cases where something else should come first, and the firm exclusions.

What Results Can You Expect From the O-Shot?

Results from the O-Shot vary with your biology, hormone status, and the concerns being treated. That said, many women report meaningful gains across several areas of sexual and pelvic health. Knowing the realistic timeline and scope of results helps set fair expectations before treatment.

How long does it take to see O-Shot results?

The O-Shot is a regenerative procedure, which means results develop over time as the tissue responds to the growth factors. Most women begin to notice early changes within 2 to 4 weeks of treatment. The full benefit often shows between 6 and 12 weeks after injection, as tissue repair, collagen remodeling, and better blood supply reach their peak.

Some women notice an early gain in lubrication and sensitivity within the first few weeks. Others see the biggest change in orgasm quality, arousal response, and urinary control in the 8 to 12 week window. Patience is part of the process. This is biology rebuilding itself, not a stimulant creating a short-term effect.

How long do O-Shot results last?

Most patients report results lasting between 12 and 18 months, though individual variation is significant. Factors that affect how long results last include hormone balance, overall tissue health, age, and whether the treatment is paired with other care such as hormone optimization.

At Arbour Longevity, many women choose a follow-up O-Shot each year to maintain their results, especially when the treatment is part of a broader sexual wellness or hormone plan.

How many O-Shot sessions are needed?

Many women report meaningful gains after a single O-Shot session. For some, a series of up to three sessions is recommended. Some patients notice encouraging changes after their first treatment, while others see the largest change in sensitivity and urinary control after a short series. Gandhi will assess your response and goals at each visit to decide the plan that fits you, rather than a set package.

Are there any O-Shot side effects or risks?

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Because the O-Shot uses PRP from your own blood, the risk of allergic reaction or rejection is very low. The most commonly reported side effects are mild and short-lived:

  • Mild swelling or sensitivity at the injection site in the first 24 to 48 hours
  • Light spotting in rare cases
  • Brief discomfort right after the procedure

Serious complications are rare when the procedure is done by a qualified, licensed clinician. This is why provider choice matters. The O-Shot at Arbour Longevity is performed by Gandhi Bhattarai under a CMA-licensed protocol, not by an aesthetician or unlicensed wellness provider.

What is the recovery process after an O-Shot?

Recovery is minimal. There is no downtime with the O-Shot. Most women return to their normal daily activities right after the procedure. Light activity and normal routines can resume the same day. You will get specific after-care guidance at your appointment, including any short-term advice around intimate activity in the first 24 to 48 hours.

Does the O-Shot really work? What patients are saying

The clinical evidence for PRP-based regenerative therapy in female sexual dysfunction is growing, though the studies are still small. Patient-reported outcomes often describe gains in sensitivity, arousal, lubrication, orgasm quality, and fewer stress incontinence symptoms.

At Arbour Longevity, the O-Shot is delivered within a clinical framework that looks at the full picture of a woman's health: hormonal, vascular, and psychological. The women who report the most benefit are often those whose treatment is tailored, clinically supervised, and supported by other care where indicated.

Why Choose Arbour Longevity for Your O-Shot in Ann Arbor?

Where you receive the O-Shot matters more than most patients first realize. The procedure itself is simple, but the clinical context around it shapes the quality, safety, and staying power of your results. Not every provider offering PRP injections for women holds the credentials, licensure, or clinical depth to deliver the O-Shot properly.

Our regenerative medicine expertise and clinical approach

Arbour Longevity is a board-certified anti-aging and regenerative medicine clinic serving Ann Arbor and Southeast Michigan. If you are weighing that approach against conventional anti-aging care, why Ann Arbor patients are choosing regenerative medicine explains the difference. The clinic is led by Gandhi Bhattarai, FNP-BC, PMHNP-BC, a Triple Board Certified Clinician holding board certifications in Family Medicine, Psychiatry, and Anti-Aging & Regenerative Medicine.

This triple-certified framework is rare in the sexual wellness space. Intimate health concerns do not exist on their own. Hormone shifts affect mood. Confidence in a relationship affects arousal. Mental wellbeing is inseparable from sexual function. Gandhi's clinical lens accounts for all of it.

Arbour Longevity is a CMA-licensed O-Shot provider, which sets the clinic apart from the growing number of medspas and wellness centers offering unlicensed PRP services under the O-Shot name. Licensure under the Cellular Medicine Association means the procedure follows established clinical standards and protocols.

What makes our O-Shot protocol different?

At Arbour Longevity, the O-Shot is never treated as a stand-alone cosmetic service. It is assessed within a full clinical framework that includes:

  • Hormone evaluation, because estrogen and testosterone levels shape how tissue responds to the O-Shot
  • Vascular and pelvic health assessment, to make sure the tissue setting supports repair
  • Psychiatric and emotional health awareness, because sexual wellness is deeply tied to mental wellbeing
  • Other treatments where clinically indicated, such as hormone optimization

This is the difference between receiving a PRP injection and receiving a truly tailored sexual wellness treatment.

What to expect at your O-Shot first visit

Your first visit at Arbour Longevity is a private, 45-minute clinical assessment with Gandhi. It covers your full health history, current symptoms, hormone status, lifestyle factors, and your goals. Nothing is rushed. Nothing is superficial.

By the end of it, you will know whether the O-Shot is the right treatment for you, what other care may support your results, and exactly what to expect from the procedure and recovery. Your first-visit fee is applied toward your treatment, so there is no financial risk in starting the conversation.

How to book your O-Shot appointment in Ann Arbor, MI

Booking is simple. Arbour Longevity is at 2217 Packard St, Suite 15, Ann Arbor, MI 48104, inside the Eastover Professional Center, with free on-site parking. The clinic is open Thursday through Monday, 10:00 AM to 7:00 PM.

You can book your private first visit online or call the clinic directly at (734) 436-3357. All O-Shot first visits are completely confidential. Arbour Longevity serves women across Ann Arbor, Detroit, Dexter, Saline, Ypsilanti, Plymouth, Canton, Northville, and throughout Southeast Michigan.

If your partner has noticed changes over the same period, it is often worth planning treatment together. Our guide to the O-Shot and P-Shot for couples explains how the two procedures are scheduled so your timelines align.

Often Asked Questions About the O-Shot

What is the O-Shot?

The O-Shot (Orgasm Shot) is a non-surgical PRP procedure that uses platelet-rich plasma from your own blood to support repair of vaginal and clitoral tissue. It aims to improve sensitivity, arousal, lubrication, and bladder control.

What does the research actually show about the O-Shot?

A 2026 systematic review in The Journal of Sexual Medicine pooled 18 studies covering 480 women, 401 of whom were treated with PRP. It reported gains in sexual function, symptoms, and vaginal health, with side effects that were few and mild. The most studied uses were vulvar lichen sclerosus, sexual dysfunction, and vulvovaginal atrophy. The authors also note that protocols still vary widely between clinics, which is exactly why preparation method and injection technique matter so much. At Arbour Longevity the O-Shot is performed under CMA licensure by a triple board certified clinician following established protocols.

How painful is the O-Shot?

Discomfort is minimal. A numbing cream is applied before the procedure, and most women report feeling only mild pressure during the injection rather than pain.

Can the O-Shot help with urinary incontinence?

Yes. The O-Shot is one of the few non-surgical treatments for stress urinary incontinence with randomized-trial support. PRP placed along the front vaginal wall supports urethral tissue and pelvic floor health, reducing leaks over time for many women.

Is there downtime after the O-Shot?

No. The O-Shot is a same-day, minimally invasive procedure with no required downtime. Most women resume normal activity right after their appointment.

How many O-Shot treatments are needed?

Some women see results from a single session. For others, up to three sessions are recommended. Gandhi will guide you through a tailored plan based on your response and goals.

Can the O-Shot help after menopause?

Yes. Postmenopausal women are often excellent candidates for the O-Shot. For the best chance of a good result, Gandhi may recommend pairing the O-Shot with hormone optimization to address both the tissue setting and the hormone factors driving symptoms.

What is the cost of the O-Shot at Arbour Longevity?

O-Shot pricing is discussed at your first visit, and your $35 first-visit fee is applied toward the treatment cost. Call (734) 436-3357 or book online for your private assessment.

Reclaim What Changed, on Your Own Terms

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Your sexual health is not a luxury concern. It is a clinical one, and it deserves the same precision and expertise applied to every other part of your wellbeing.

The O-Shot at Arbour Longevity is not a quick-fix injection at a wellness pop-up. It is a clinically supervised, CMA-licensed regenerative procedure, performed by a triple board certified clinician, within a framework that sees you as a whole person rather than a symptom to treat.

If something has changed and you are ready to understand why and do something about it, the conversation starts with a private, 45-minute first visit with Gandhi Bhattarai at Arbour Longevity in Ann Arbor. Book your $35 first visit online or call (734) 436-3357; the $35 is applied toward your plan.

References

  1. De Ponte A, Cabrera S, Bermúdez Sparice SS, Baulies S, Rodríguez I. Platelet-rich plasma in the management of vulvovaginal disorders: a systematic review. The Journal of Sexual Medicine. 2026;23(1). PMID 41168677. doi:10.1093/jsxmed/qdaf307

This content is educational and does not constitute medical advice. The O-Shot requires clinical evaluation and is not appropriate for everyone. Individual results vary.

Gandhi Bhattarai, FNP-BC, PMHNP-BC

Gandhi Bhattarai, FNP-BC, PMHNP-BC, Anti-Aging/Functional Medicine BC

Triple board-certified nurse practitioner and founder of Arbour Longevity in Ann Arbor. Every article is written from clinic practice and reviewed against current guidelines.

✓ Medically reviewed · Last updated August 21, 2026

How we reviewed this article

Arbour Longevity articles are written by the treating clinician, checked against primary sources (peer-reviewed journals, FDA labeling, Endocrine Society and other specialty guidelines) and re-reviewed when guidance changes. See our editorial policy. Spotted an error? Email info@arbourlongevity.com.

This article is educational and is not a substitute for individualized medical advice. Whether a treatment is appropriate for you is determined during consultation.

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