O-Shot in Ann Arbor, MI - Restore Intimacy & Sexual Wellness Naturally

The O-Shot (Orgasm Shot) is a regenerative PRP procedure designed specifically for women experiencing sexual dysfunction, vaginal dryness, low libido, reduced sensitivity, or stress urinary incontinence. At Arbour Longevity in Ann Arbor, Michigan, the O-Shot is administered within a complete clinical framework that considers your hormonal health, vascular function, and overall wellness, not just the symptom in isolation.

This is not a temporary fix. It is tissue-level regeneration using your own biology.

What Is the O-Shot and How Does It Work?

The O-Shot, short for Orgasm Shot, is a non-surgical, same-visit PRP procedure that uses platelet-rich plasma derived from your own blood to stimulate tissue regeneration in the clitoral and vaginal region. First developed within the field of regenerative medicine, the procedure applies the same biological principles used in orthopedic and aesthetic PRP therapy, the ability of concentrated growth factors to trigger cellular repair, collagen stimulation, and improved tissue function.

It is not a drug. It contains no synthetic hormones, no foreign substances, and no chemical compounds. Every component comes directly from your own bloodstream.

Because every component is autologous, the biology doing the work is your own repair system, concentrated and delivered exactly where it is needed. A 2026 systematic review in the Journal of Sexual Medicine pooled 18 studies covering 480 women, 401 of them treated with PRP, and reported improvements in sexual function, symptoms, and vaginal health, with adverse events that were few and mild. That is a strong showing for a same-visit, non-surgical procedure, and it is consistent with what we see in patients here.

What Does PRP Therapy Have to Do With the O-Shot?

Platelet-rich plasma therapy has been used in regenerative medicine for decades. The foundation of the treatment is straightforward: your blood contains platelets that carry concentrated growth factors, proteins responsible for tissue healing, collagen production, cellular regeneration, and improved blood flow.

When those growth factors are extracted, concentrated, and reintroduced into a specific area of the body, they accelerate the body's natural repair process in that targeted tissue. In orthopedics, PRP is used for joint repair. In aesthetics, it is used for skin rejuvenation - the Vampire Facelift applies the same platelet biology to the face. In the O-Shot, those same regenerative mechanisms are applied to vaginal and clitoral tissue to restore sensitivity, lubrication, and function.

How Is Platelet-Rich Plasma Extracted and Prepared?

The process begins with a standard blood draw, the same as any routine lab visit. That blood sample is then placed into a centrifuge, a device that spins at high speed to separate the blood into its components. The result is a concentrated layer of platelet-rich plasma sitting above the red blood cells. This PRP is then carefully drawn into a syringe and prepared for injection. The entire preparation happens in-office, during your appointment, and takes only a few minutes.

How Do Growth Factors Trigger Tissue Regeneration?

Once injected into the targeted tissue, the growth factors within the PRP initiate a cascade of biological activity. They signal the body to produce new collagen, promote the formation of new blood vessels (a process called angiogenesis), and stimulate the activity of stem cells already present in the local tissue. This results in improved tissue thickness, increased vascular supply, enhanced nerve sensitivity, and better natural lubrication over time. The response is gradual and cumulative, the body is rebuilding, not just responding to a stimulant.

What Happens During an O-Shot Procedure at Arbour Longevity?

At Arbour Longevity, the O-Shot is administered by Gandhi Bhattarai, FNP-BC, PMHNP-BC, a Triple Board Certified Clinician in Family Medicine, Psychiatry, and Anti-Aging & Regenerative Medicine. Arbour Longevity is a CMA-licensed provider for the O-Shot, which distinguishes the clinic from standard medspas offering unlicensed or unverified PRP services.

Your appointment begins with a private consultation covering your clinical history, hormonal status, symptoms, and goals. The procedure itself follows a clear, comfortable sequence.

Is the O-Shot Painful? What Should You Expect Step by Step?

Discomfort is minimal. A topical anesthetic cream is applied to the treatment area well before the injection to ensure the experience is as comfortable as possible. Most patients report feeling only mild pressure during the procedure, not pain. Here is what the process looks like from start to finish:

Blood draw: A small amount of blood is drawn from your arm, identical to a routine lab test.

PRP preparation: The blood sample is placed in the centrifuge in-office and spun down to isolate the platelet-rich plasma.

Topical anesthetic application: A numbing cream is applied to the clitoral and vaginal area and given time to take full effect.

Injection: The concentrated PRP is carefully injected into the clitoral region and the anterior vaginal wall (the area associated with the G-spot and urethral support).

Recovery: There is no downtime. Most patients return to normal activity the same day.

How Long Does the O-Shot Procedure Take?

From start to finish, the entire appointment typically takes 45 to 60 minutes, including consultation, blood draw, PRP preparation, and the procedure itself. Because it is a same-visit treatment, there is no need for multiple pre-procedure appointments or lengthy preparation protocols.

What Conditions Can the O-Shot Treat?

The O-Shot is not a single-symptom solution. Its regenerative mechanism addresses multiple overlapping concerns that affect female sexual health, pelvic function, and intimate wellness. Women seek the O-Shot for a range of conditions, from reduced arousal after childbirth to vaginal dryness following menopause.

Understanding what the O-Shot can address helps clarify whether it is the right starting point for your specific concerns.

Can the O-Shot Help With Low Libido and Arousal Difficulties?

Low libido and difficulty with arousal are among the most common and most under-discussed concerns in women's sexual health. They are not simply psychological. Reduced blood flow to the clitoral and vaginal tissue, hormonal shifts, and tissue thinning all contribute to a measurable decline in physical arousal response.

The O-Shot targets this at the tissue level. By improving vascular supply and nerve sensitivity in the clitoral region, many women report a meaningful improvement in arousal response, sexual desire, and ease of reaching orgasm. The treatment supports the physical infrastructure that makes intimacy feel the way it should.

How Does Menopause Impact Female Sexual Function?

Menopause brings a sharp decline in estrogen and testosterone, two hormones that are directly responsible for vaginal tissue health, lubrication, and sexual response. As estrogen drops, the vaginal walls become thinner, drier, and less elastic, a condition known as vaginal atrophy. Sensitivity decreases. Arousal becomes slower and less reliable. Intercourse can become uncomfortable or outright painful.

At Arbour Longevity, the O-Shot is often assessed alongside hormone optimization, including BHRT (bioidentical hormone replacement therapy) because addressing the hormonal environment while simultaneously regenerating local tissue produces significantly better outcomes than either approach alone. This is the clinical difference that a whole-person framework delivers.

Does the O-Shot Treat Stress Urinary Incontinence?

Yes, and this is one of the most clinically supported benefits of the O-Shot. Stress urinary incontinence (SUI) refers to the involuntary leakage of urine during physical activity, coughing, sneezing, laughing, or exercising. It is caused by weakened pelvic floor support and compromised urethral tissue, often following childbirth, hormonal changes, or aging.

The PRP injected during the O-Shot stimulates tissue regeneration along the anterior vaginal wall, which provides structural support to the urethra. As the tissue thickens and strengthens over the weeks following treatment, many women experience a significant reduction in stress incontinence episodes. For women who have been managing this condition quietly, avoiding workouts, planning around bathroom access, or simply accepting it, the O-Shot offers a non-surgical path toward genuine improvement.

Bladder leakage is a deep enough topic on its own that we gave it a dedicated page: the O-Shot for stress urinary incontinence covers the randomized, sham-controlled trial evidence, how an incontinence course is spaced, and where surgery is still the better option.

Can the O-Shot Relieve Vaginal Dryness and Painful Intercourse?

Vaginal dryness and dyspareunia (painful intercourse) are directly related to inadequate tissue health and insufficient natural lubrication. Both conditions are common during perimenopause and menopause but can also occur in younger women due to hormonal imbalances, postpartum changes, or certain medications.

The growth factors delivered through the O-Shot promote the restoration of vaginal tissue thickness, improved glandular function, and increased natural lubrication over time. Many patients report noticeable improvement in comfort during intercourse within several weeks of treatment, with continued improvement as the regenerative process matures. Pain during sex has several possible causes and is worth working through properly - sexual pain in women is treatable sets out what else to rule out first.

Who Is an Ideal Candidate for the O-Shot?

The O-Shot is appropriate for a broad range of women experiencing changes in sexual function or pelvic health. You may be a strong candidate if you are experiencing any of the following:

• Reduced sexual sensitivity or difficulty reaching orgasm
• Low libido or diminished sexual desire
• Vaginal dryness, especially after menopause or hormonal changes
• Painful intercourse (dyspareunia)
• Stress urinary incontinence leaking with coughing, sneezing, or exercise
• Postpartum changes in sensation or vaginal tissue tone
• Sexual arousal disorder or difficulty becoming physically aroused
• A desire to enhance sexual satisfaction and intimacy confidence

The O-Shot is suitable for women across a wide age range, from those experiencing postpartum changes in their 30s to women navigating perimenopause and menopause in their 40s, 50s, and beyond.

Those two life stages involve genuinely different tissue changes and different treatment sequences. If one of them is your reason for reading, see the O-Shot after childbirth and after menopause, which explains what changes in each case and why hormones come first after menopause.

Who Should Avoid the O-Shot Treatment?

The O-Shot is generally very well-tolerated, but it is not appropriate for everyone. A thorough consultation with Gandhi at Arbour Longevity will determine whether the treatment is right for you. Contraindications may include active infection in the treatment area, blood clotting disorders, active cancer, or certain platelet abnormalities. This is exactly why the O-Shot at Arbour Longevity begins with a complete clinical assessment, not a simple booking form.

If you would like to work through this before your visit, our screening guide to O-Shot candidacy - who it helps and who it does not sets out the concerns it matches best, the situations where something else should come first, and the absolute contraindications.

What Results Can You Expect From the O-Shot?

Results from the O-Shot vary based on individual biology, hormonal status, and the specific concerns being addressed. That said, many women report meaningful improvements across several areas of sexual and pelvic health. Understanding the realistic timeline and scope of results helps set accurate expectations before treatment.

How Long Does It Take to See O-Shot Results?

The O-Shot is a regenerative procedure, which means results develop over time as the tissue responds to the growth factors. Most women begin to notice initial changes within 2 to 4 weeks of treatment. The full benefit of the procedure typically becomes apparent between 6 to 12 weeks post-injection, as tissue regeneration, collagen remodeling, and improved vascular supply reach their peak.

Some women notice an early improvement in lubrication and sensitivity within the first few weeks. Others experience the most significant improvements in orgasm quality, arousal response, and urinary control in the 8 to 12 week window. Patience is part of the process, this is biology rebuilding itself, not a stimulant creating a temporary effect.

How Long Do O-Shot Results Last?

Most patients experience results that last between 12 to 18 months, though individual variation is significant. Factors that influence longevity of results include hormonal balance, overall tissue health, age, and whether the treatment is combined with complementary therapies such as hormone optimization.

At Arbour Longevity, many women choose to schedule a follow-up O-Shot annually to maintain and compound their results over time, particularly when the treatment is integrated into a broader sexual wellness or hormone optimization protocol.

How Many O-Shot Sessions Are Needed?

Many women experience meaningful improvement after a single O-Shot session. However, for the most dramatic and lasting results, a series of up to three sessions is recommended. Some patients notice encouraging changes after their first treatment, but clinical experience consistently shows that the most significant tissue regeneration, sensitivity restoration, and urinary control improvements are achieved through up to three sessions spaced appropriately over time. Gandhi will assess your individual response and goals at each visit to determine the optimal treatment plan for you.

Are There Any O-Shot Side Effects or Risks?

Because the O-Shot uses your own blood-derived PRP, the risk of allergic reaction or rejection is essentially nonexistent. The most commonly reported side effects are mild and temporary:

• Mild swelling or sensitivity at the injection site in the first 24 to 48 hours
• Temporary spotting in rare cases
• Brief discomfort immediately following the procedure

Serious complications are extremely rare when the procedure is performed by a qualified, licensed clinician. This is why provider selection matters significantly. The O-Shot at Arbour Longevity is administered by Gandhi Bhattarai under a CMA-licensed protocol, not by an aesthetician or unlicensed wellness provider.

What Is the Recovery Process After an O-Shot?

Recovery is minimal. There is no downtime associated with the O-Shot. Most women return to their normal daily activities immediately after the procedure. Light activity and normal routines can be resumed the same day. Specific post-procedure guidance will be provided at your appointment, including any temporary recommendations around intimate activity in the first 24 to 48 hours.

Does the O-Shot Really Work? What Patients Are Saying

The clinical evidence supporting PRP-based regenerative therapy for female sexual dysfunction is growing steadily. Patient-reported outcomes consistently reflect improvements in sensitivity, arousal, lubrication, orgasm quality, and reduction in stress urinary incontinence symptoms.

At Arbour Longevity, the O-Shot is delivered within a clinical framework that addresses the full picture of a woman's health, hormonal, vascular, and psychological. This approach produces outcomes that stand-alone PRP procedures at non-clinical settings cannot replicate. The women who see the most significant results are typically those whose treatment is personalized, clinically supervised, and appropriately supported by complementary therapies where indicated.

Why Choose Arbour Longevity for Your O-Shot in Ann Arbor?

Choosing where to receive the O-Shot matters more than most patients initially realize. The procedure itself is straightforward but the clinical context surrounding it determines the quality, safety, and longevity of your results. Not every provider offering PRP injections for women holds the credentials, licensure, or clinical depth to deliver the O-Shot properly.

Our Regenerative Medicine Expertise and Clinical Approach

Arbour Longevity is Ann Arbor and Southeast Michigan's only board-certified anti-aging and regenerative medicine clinic. If you are weighing that approach against conventional anti-aging care, why Ann Arbor patients are choosing regenerative medicine explains the difference. The clinic is led by Gandhi Bhattarai, FNP-BC, PMHNP-BC, a Triple Board Certified Clinician holding board certifications in Family Medicine, Psychiatry, and Anti-Aging & Regenerative Medicine.

This triple-certified clinical framework is rare in the sexual wellness space. Intimate health concerns do not exist in isolation. Hormonal shifts affect mood. Relationship confidence affects arousal. Psychological wellbeing is inseparable from sexual function. Gandhi's clinical lens accounts for all of it.

Arbour Longevity is a CMA-licensed O-Shot provider, which distinguishes the clinic from the growing number of medspas and wellness centers offering unlicensed PRP services under the O-Shot name. Licensure under the Cellular Medicine Association ensures that the procedure meets established clinical standards and protocols.

What Makes Our O-Shot Protocol Different?

At Arbour Longevity, the O-Shot is never treated as a standalone cosmetic service. It is assessed within a complete clinical framework that includes:

• Hormonal evaluation because optimal estrogen and testosterone levels significantly amplify O-Shot results
• Vascular and pelvic health assessment to ensure the tissue environment supports regeneration
• Psychiatric and emotional health awareness because sexual wellness is deeply connected to psychological wellbeing
• Complementary treatment integration including PT-141, Kisspeptin, and hormone optimization protocols where clinically indicated - the two peptides work differently, as Kisspeptin versus PT-141 explains

This is the clinical difference between receiving a PRP injection and receiving a genuinely personalized sexual wellness treatment.

What to Expect at Your O-Shot Consultation

Your consultation at Arbour Longevity is a private, 45-minute clinical assessment with Gandhi. It covers your full health history, current symptoms, hormonal status, lifestyle factors, and your goals. Nothing is rushed. Nothing is superficial.

By the end of your consultation, you will have a clear understanding of whether the O-Shot is the right treatment for you, what complementary therapies may enhance your results, and exactly what to expect from the procedure and recovery. Your consultation fee is applied toward your treatment, there is no financial risk to starting the conversation.

How to Book Your O-Shot Appointment in Ann Arbor, MI

Booking is straightforward. Arbour Longevity is located at 2217 Packard St, Suite 15, Ann Arbor, MI 48104, inside the Eastover Professional Center, with free on-site parking. The clinic is open Thursday through Monday, 10:00 AM to 7:00 PM.

You can book your private consultation online or call the clinic directly at (734) 436-3357. All O-Shot consultations are completely confidential. Arbour Longevity serves women across Ann Arbor, Detroit, Dexter, Saline, Ypsilanti, Plymouth, Canton, Northville, and throughout Southeast Michigan.

If your partner has noticed changes over the same period, it is often worth planning treatment together. Our guide to the O-Shot and P-Shot for couples explains how the two procedures are scheduled so your timelines align.

Frequently Asked Questions About the O-Shot

What is the O-Shot? 

The O-Shot (Orgasm Shot) is a non-surgical PRP procedure that uses platelet-rich plasma from your own blood to regenerate vaginal and clitoral tissue, improving sensitivity, arousal, lubrication, and urinary continence.

What does the research actually show about the O-Shot? 

A 2026 systematic review in the Journal of Sexual Medicine pooled 18 studies covering 480 women, 401 of whom were treated with PRP, and reported improvements in sexual function, symptoms, and vaginal health, with adverse events that were few and mild. The most frequently studied indications across those studies were vulvar lichen sclerosus, sexual dysfunction, and vulvovaginal atrophy. The authors also note that protocols still vary widely between clinics, which is exactly why preparation method and injection technique matter so much. At Arbour Longevity the O-Shot is performed under CMA licensure by a triple board certified clinician following established clinical protocols.

How painful is the O-Shot? 

Discomfort is minimal. A topical numbing cream is applied before the procedure, and most women report feeling only mild pressure during the injection rather than pain.

Can the O-Shot help with urinary incontinence? 

Yes. The O-Shot is one of the most clinically recognized non-surgical treatments for stress urinary incontinence. PRP injected along the anterior vaginal wall supports urethral tissue and pelvic floor health, reducing leakage over time.

Is there downtime after the O-Shot? 

No. The O-Shot is a same-day, minimally invasive procedure with no required downtime. Most women resume normal activity immediately after their appointment.

How many O-Shot treatments are needed? 

Some women experience results from a single session. However, for the most dramatic outcomes, up to three sessions are recommended. Gandhi will guide you through an individualized treatment plan based on your response and goals.

Can the O-Shot help after menopause? 

Yes. Postmenopausal women are often excellent candidates for the O-Shot. For the best results, Gandhi may recommend combining the O-Shot with hormone optimization to address both the tissue environment and the underlying hormonal factors driving symptoms.

What is the cost of the O-Shot at Arbour Longevity? The O-Shot at Arbour Longevity is priced at $1,500. Your consultation fee is applied toward the treatment cost. Call (734) 436-3357 or book online for your private assessment.

Reclaim What Changed - On Your Own Terms

Your sexual health is not a luxury concern. It is a clinical one and it deserves the same precision and expertise applied to every other aspect of your wellbeing.

The O-Shot at Arbour Longevity is not a quick-fix injection at a wellness pop-up. It is a clinically supervised, Triple Board Certified, CMA-licensed regenerative procedure delivered within a complete framework that sees you as a whole person, not just a symptom to treat.

If something has changed and you are ready to understand why and do something about it, the conversation starts with a private, 45-minute consultation with Gandhi Bhattarai at Arbour Longevity in Ann Arbor.

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